Korean Journal of Veterinary Research (대한수의학회지)
- Volume 36 Issue 2
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- Pages.337-348
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- 1996
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
Subpopulation in periopheral blood leukocyte of Korean native cattle by using monoclonal antibodies specific to bovine leukocyte differentiation antigen
백혈구 표면항원 특이 단크론항체를 이용한 한우의 말초혈액 백혈구 아군에 관한 연구
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Moon, Jin-san
(Veterinary Research Institute) ;
-
Park, Yong-ho
(College of Veterinary Medicine, Seoul National University) ;
- Jung, Suk-chan (Veterinary Research Institute) ;
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Ku, Bok-gyeong
(Veterinary Research Institute) ;
- Kang, Byong-kyu (College of Veterinary Medicine, Chonnam National University)
-
문진산
(농촌진흥청 수의과학연구소) ;
-
박용호
(서울대학교 수의과대학) ;
- 정석찬 (농촌진흥청 수의과학연구소) ;
-
구복경
(농촌진흥청 수의과학연구소) ;
- 강병규 (전남대학교 수의과대학)
- Received : 1995.11.24
- Published : 1996.06.25
Abstract
The proportion of leukocyte subpopulation in the host is of a great importance in understanding their functions and disease progress. Many methods have been developed to seperate leukocytes and to measure their activities. Characterization of immune cell subpopulations in Korean native cattle was performed using a set of monoclonal antibodies specific which are specific to bovine leukocyte differentiation antigen. Peripheral blood leukocytes from fifty Korean native and ten Holstein cattle were collected and analyzed for the investigation of leukocyte subpopulation by using monoclonal antibodies and flow cytometry. The result indicated that Korean native cattle have significantly higher proportion of leukocyte subpopulations expressing MHC class II molecules and BoCD4 than Holstein cattle.
Keywords
- Korean native cattle;
- leukocyte differentiation molecules;
- major histocompatibility complex;
- cluster differentiation