A Case of Cryptococcal Lymphadenitis Mimicking Lymphoma

정상아에서 Lymphoma로 혼동된 Cryptococcal Lymphadenitis 1례

  • Kim, Bo Mi (Department of Pediatrics, College of Medicine, Hallym University) ;
  • Min, Ki Sik (Department of Pediatrics, College of Medicine, Hallym University) ;
  • Kim, Jong Wan (Department of Pediatrics, College of Medicine, Hallym University) ;
  • Kim, Kwang Nam (Department of Pediatrics, College of Medicine, Hallym University) ;
  • Ryoo, Ki Yang (Department of Pediatrics, College of Medicine, Hallym University)
  • 김보미 (한림대학교 의과대학 소아과학교실) ;
  • 민기식 (한림대학교 의과대학 소아과학교실) ;
  • 김종완 (한림대학교 의과대학 소아과학교실) ;
  • 김광남 (한림대학교 의과대학 소아과학교실) ;
  • 유기양 (한림대학교 의과대학 소아과학교실)
  • Published : 1996.11.20

Abstract

Cryptococcosis is a rare in normal child and the majority of cases usually occur in patients with defective cell-mediated immunity. Infection is acquired by inhalation of organisms from the environment and disseminated via the blood stream to any organ of the body. We experienced a 7 year old girl who presented with fever, both cervical lymphadenopathy, hepatomegaly under the impression of lymphoma. However lymph node biopsy revealed cryptococcal budding and culture of lymph nodes yielded cryptococcus neoformans. The radiologic finding showed huge, multiple cervical lymph node enlargement spreading to mediastinum and abdomen. The immune fuction in term of T cell, B cell, serum immunoglobulin, complement and neutrophil function tests was normal. The patient was treated with amphotericin B and flucytosine for 6 weeks and responded to the treatment well. We report this case with brief review of the related literatures.

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