Synthesis and Antitumor Activity of Cannabigerol

  • Baek, Seung-Hwa (Department of Chemistry and Department of Oral Anatomy, Wonkwang University) ;
  • Han, Du-Seok (Department of Chemistry and Department of Oral Anatomy, Wonkwang University) ;
  • Yook, Chan-Nam (Department of Health Hygienic, Wonkwang Public Health Junior College) ;
  • Kim, Young-Chae (Department of Chemistry and Department of Oral Anatomy, Wonkwang University) ;
  • Kwak, Jung-Suk (Department of Chemistry and Department of Oral Anatomy, Wonkwang University)
  • Published : 1996.06.01

Abstract

Cannabigerol(3) was synthesized and evaluated for its inhibitory activity against mouse skin melanoma cells. Cannabigerol displayed significant antitumor activity [inhibitory concentration $(IC_{50})=31.31\mug/mL]$ in vitro assay.

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