The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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Naloxone Reversal of He-Ne Laser Stimulation Induced Analgesia in Rat

헬륨 -네온 레이저자극으로 유발된 흰쥐 진통작용의 날록손 반전

  • Lee Jae-Hyoung (Department of Physical Therapy, Wonkwang Health Junior College) ;
  • Song In-Yong (Department of Physical Therapy, Wonkwang Health Junior College) ;
  • Choi Eun-Yong (Department of Rehabilitation, Kwangyang Junior College)
  • 이재형 (원광보건전문대학 물리치료과) ;
  • 송인영 (원광보건전문대학 물리치료과) ;
  • 최은영 (광양전문대학 재활학과)
  • Published : 1996.08.01
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Abstract

The purpose of this study were to 1) determine the analgesic effect of 632.8 nm of helium-neon (He-Ne) laser stimulation on acupuncture point in rat and 2) determine the reversal of analgesic effect by naloxone injection. Eighteen Sprague-Dawley rats were devided into three groups : control (n=6) : laser (n=6), laser stimulation at $3.58\;J/cm^2$ ; and naloxone (n=6), 1 mg/kg of naloxone chloride inject into peritoneum before laser stimulation at $3.63J/cm^2$. Tail-flick latency were measured pretreat and posttreat with hot plate $(55^{\circ}C)$. Data were analyzed using one-way ANOVA and paired t-teat for tail-flick latency. No significant change was noted in the tail-flick latency in either control or naloxone groups. But significant increased in tail-flick latency in taller group. The results suggest that He-Ne laser induced analgesic effect, and endogenous opioids may be involved in He-Ne laser induced analgesia.

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