Thymoma accompanying Autoimmune Hemolytic Anemia

자가 용혈성 빈혈을 동반한 흉선종 1예

  • Lee, Sin-Hwa (Department of Internal Medicine, Kosin Medical College) ;
  • Park, Neung-Hwa (Department of Internal Medicine, Kosin Medical College) ;
  • Lee, Keum-Hee (Department of Internal Medicine, Kosin Medical College) ;
  • Kim, Young-Woo (Department of Internal Medicine, Kosin Medical College) ;
  • Jang, Tai-Weon (Department of Internal Medicine, Kosin Medical College) ;
  • Jung, Maan-Hong (Department of Internal Medicine, Kosin Medical College) ;
  • Jung, Gyoo-Sik (Department of Radiology, Kosin Medical College) ;
  • Cho, Sung-Rae (Department of Thoracic Surgery, Kosin Medical College)
  • Published : 1995.06.30

Abstract

Severe autoimmune hemolytic anemia was developed in the 45-year-old man whose anterior mediastinal growing mass, which was proved later as the invasive thymoma, had been found 4 years ago. The hemoglobin level was 6.2g/dl and both the direct and indirect Coombs' tests were positive. Prompt remission of the hemolytic anemia was achieved by thymectomy combined with corticosteroid therapy. Two months after the discontinuation of corticosteroid therapy his hemolytic anemia was recurred. The patient currently has been followed up for 8 months with no signs of local recurrence or hemolytic anemia and he is still receiving 15 mg of prednisolone daily.

45세의 침윤형 흉선종 환자에서 혈색소는 6.2g/dl, 직접 및 간접 Coombs' test는 모두 양성인 심한 자가 면역 용혈성 빈혈이 동반되어 있었다. 흉선종 적출술과 부신피질호르몬제의 투여로 용혈성 빈혈의 호전이 보였으나 부신피질호르몬제를 중단한 2달후에 용혈성 빈혈이 재발되어 현재 prednisolone 15mg/day을 투여 중이며 국소재발이나 용혈성 빈혈의 소견없이 8개월째 경과관찰 중이다.

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