Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)
- Volume 5 Issue 1
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- Pages.40-47
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- 1995
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- 2384-132X(pISSN)
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- 2289-0564(eISSN)
Chromosome Aberrations of Styrene Exposed Workers
스티렌 취급근로자의 염색체이상연구
- Maeng, Seung Hee (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
- Kang, Sung Kyu (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
- Yang, Jung Sun (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
- Lee, Jong Sung (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
- Yu, Il Je (Industrial Health Research Institute, Korea Industrial Safety Corporation)
- 맹승희 (한국산업안전공단 산업보건연구원) ;
- 강성규 (한국산업안전공단 산업보건연구원) ;
- 양정선 (한국산업안전공단 산업보건연구원) ;
- 이종성 (한국산업안전공단 산업보건연구원) ;
- 유일재 (한국산업안전공단 산업보건연구원)
- Published : 1995.05.30
Abstract
We analyzed sytrene concentrations in air and in blood, mandelic acid in urine, and chromosome aberrations in peripheral lymphocytes of twenty one styrene-exposed workers in two reinforced plastic factories. In addition, in vitro testing for chromosome aberration was carried out. The dose-dependent clastogenicity of styrene was confirmed in the cultured Chinese hamster lung cell(CHL) with metabolic activation. The environmental styrene concentrations and urinary mandelic acid levels of analyzed subjects were different in two plants examined, but the exposure levels in most workers examined were lower than the permissible exposure levels. Chromosome aberrations of the styrene exposed workers showed no increase in the percentage of aberrant cells as compared with the control group. No correlation was found between the exposure levels and the frequencies of chromosome aberrations in workers.