Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

A STUDY ON THE EFFECT OF LSOLATED NERVE SEGMENT ON PERIPHERAL NERVE REGENERATION USING SILICONE TUBE

SILICONE TUBE에 삽입된 신경절편이 말초신경 결손부의 재생에 미치는 효과

  • Hong, Chang-Soo (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Park, No-Boo (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Jang, Hyun-Jung (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
  • 홍창수 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 박노부 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 장현중 (경북대학교 치과대학 구강악안면외과학교실)
  • Published : 1995.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study is to observe the stimulant effect of the isolated nerve segment on the peripheral nerve regeneration using silicone tube in rats. Sprague-Dawley female albino rats were used as experimental animals and nerve defects were made by resection of 14 mm-long segment of right sciatic nerves. In control group, the defects were bridged with the silicone tubes. In experimental group, the defects were bridged with the same manner and additionally, 2mm-long nerve segments were inserted at the center of the silicone tubes. 3 months later, the regenerated nerve tissue within the silicone tubes were examined by histologic study. Axonal diameters and numbers of axons were measured and all data were analyzed by using SAS package program. The results obtained were as follows : 1. The experimental group was increased than the control group in general diameters of the regenerated nerve fiber.(P<0.05) 2. The diameters of axons were increased in the experimental group compare to the control group.(P<0.05) 3. The numbers of axons were increased in the experimental group compare to the control group.(P<0.05)

Keywords