The Korean Journal of Food And Nutrition (한국식품영양학회지)
- Volume 7 Issue 4
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- Pages.383-391
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- 1994
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- 1225-4339(pISSN)
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- 2287-4992(eISSN)
Inhibitory Activity of Korean Ginseng on Lipolytic Action of Toxohormone-L from Cancerous Ascites Fluid
고려인삼이 암독소의 지방분해작용에 미치는 저해활성
- Sung-Dong Lee (Dept. of Food and Nutrition, Junior Callege of Allied Health Sciences, Korea University, Seoul 136-705, Korea) ;
- Yoo (Dept. of Home Economics, Graduate School, Korea University, Seoul 136-701, Korea, 2nd Department of Medical Biochemisttry, School of Medicine, Ehime University, Ehime 791-02, Japan)
- Published : 1994.12.01
Abstract
A substance that inhibit the lipolytic action of Toxohormone-L was a crude acidic polysaccharide isolated from Korean red and white ginseng. The total inhibitory activities (units) of PGI and PG4 fraction in white ginseng and those of PG,, PG4 and PG43 fraction in red ginseng were higher than other fractions in vitro test. Each water extract of ginseng was effective against the lipolysis induced by the Toxohormone-L at the concentration over 10~100
한국 홍삼과 백삼의 조산성 다당체 성분과 수용성 추출물, 그리고 ginsenoside 성분이 암독소 호르몬-L에 의해 유도된 지방 분해를 저해하는 효과를 검토하고자 본 연구를 수행하였다. 지방분해 및 식욕억제 인자로 알려진 암독소 호르몬-L은 saroma-180을 접종한 mouse의 복수액으로부터 부분정제하여 사용하였다. 한국 홍삼과 백삼으로부터 정ㅇ제하여 얻은 조산성 다당체 각 분획의 성분은 10