Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

A STUDY OF COMPARATIVE GROWTH DYNAMICS AND TOTAL PROTEINS BETWEEN GRANULATION TISSUE FIBROBLASTS AND NORMAL FIBROBLASTS

만성 염증시 치주 결체조직 세포 성장 및 총 단백질 변화에 관한 연구

  • Lim, Jeong-Su (Dept. of Periodontology, College of Dentistry, Chonbuk National University) ;
  • Oh, Kwi-Ok (Dept. of Phamacology, Chonbuk National University) ;
  • Kim, Hyung-Sup (Dept. of Periodontology, College of Dentistry, Chonbuk National University)
  • 임정수 (전북대학교 치과대학 치주과학교실) ;
  • 오귀옥 (전북대학교 치과대학 약리학교실) ;
  • 김형섭 (전북대학교 치과대학 치주과학교실)
  • Published : 1993.04.30
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Abstract

The investigation was undertaken to determin the altered function and structure of granulation tissue fibroblasts. Human granulation-tissue fibroblasts were cultured from periodontal chronic inflammatory lesions (SBI index : above 3) and compared with healthy gingival connective tissues fibroblasts a control(SBI index : below 1). Granulation tissue fibroblasts proliferated with a slower growth rate and exhibited larger cell size than control cells. Total protein profile of granulation tissue fibroblasts was almost identical to that of control cells with some exception. These results support tha theory that granulation tissue fibroblasts represent a distinct phenotype of fibrotic cells.

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