Archives of Pharmacal Research
- Volume 16 Issue 2
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- Pages.152-154
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- 1993
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Hofmann Rearrangement by Using N-bromophthalimide-Silveracetate in DMF
-
Park, Min-Soo
(College of Pharmacy, Kyungsung University)
;
- Choi, Chang-Uk (College of Pharmacy, Kyungsung University)
- Published : 1993.06.01
Abstract
By using N-bromophthalimide (NBP) as halonium ion source for the Hofmann rearrangement, a series of primary amide could be ocnverted to the corresponding cabamate in excellent yields. So NBP was throught to be very effective and practical halonium ion source for the Hofmann rearrangement.
Keywords
- N-bromophthalimide;
- N-bromosuccinimide;
- Dibromantine;
- Hofmann rearragement;
- Primary amide;
- Carbamate;
- Halonium ion