Toxicological Research

  • 제8권1호
  • /
  • Pages.139-143
  • /
  • 1992
  • /
  • 1976-8257(pISSN)
  • /
  • 2234-2753(eISSN)
한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

ANTIGENICITY TEST OF COPTIS RHIZOME AND CROTON TIGLIUM L. EXTRACTS(CP-2) IN GUINEA PIG AND RABBITS

  • Kang, Kyung-Sun (College of Veterinary Medicine Seoul National University) ;
  • Cho, Jae-Jin (College of Veterinary Medicine Seoul National University) ;
  • Kim, Hyung-Ook (College of Veterinary Medicine Seoul National University) ;
  • Lee, Yong-Soon (College of Veterinary Medicine Seoul National University) ;
  • Lim, Yoon-Kyu (College of Agriculture Cheju National University)
  • 발행 : 1992.06.01
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초록

Antigenicity tests-ASA(Active Systemic Anaphylaxis), PSA(Passive Systemic Anaphylaxis), PCA(Passive Cutaneous Anaphylaxis)-of CP-2(Green cross Co). were performed according to the established regulations of National Institute of Safety Research. The results were as follows. 1. No specic clinical signs related anaphylaxis were observed, therefore, it was considered that CP-2 had not antigenicity in guinea pigs and rabbits. 2. No blue spots were observed on the back of guinea pig in the PCA test` CP-2 related IgE was not produced.

키워드

참고문헌

  1. Kor. J. Food Hygine v.6 기니픽과 토끼에서 소성장홀몬(BST)의 항원성에 관한 시험 강경선;이영순
  2. Environmental Mutagen & Carcinogenesis v.11 기니픽과 도끼에서 PDT-Hepa의 항원성 시험 강경선;이영순
  3. 독성시험에 관한 지침 국립보건안전 연구원 예규