Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Inhibitory Activity against Protein Kinase C of Some Medicinal Plants

수종 생약의 Protein kinase C 저해활성

  • Lee, Hyun-Sun (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST) ;
  • Ahn, Soon-Cheol (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST) ;
  • Kim, Bo-Hyun (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST) ;
  • Park, Moon-Su (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST) ;
  • Oh, Won-Keun (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST) ;
  • Yoon, Byung-Dae (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST) ;
  • Ahn, Jong-Seog (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST) ;
  • Mheen, Tae-Ick (Laboratory of Microbial Technology, Genetic Engineering Research Institute, KIST)
  • 이현선 (한국과학기술연구원 유전공학연구소) ;
  • 안순철 (한국과학기술연구원 유전공학연구소) ;
  • 김보연 (한국과학기술연구원 유전공학연구소) ;
  • 박문수 (한국과학기술연구원 유전공학연구소) ;
  • 오원근 (한국과학기술연구원 유전공학연구소) ;
  • 윤병대 (한국과학기술연구원 유전공학연구소) ;
  • 안종석 (한국과학기술연구원 유전공학연구소) ;
  • 민태익 (한국과학기술연구원 유전공학연구소)
  • Published : 1992.09.30
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Abstract

MeOH extract of twenty medicinal herbs were screened for their effects against protein kinase C (PKC) using bleb-forming assay and PKC enzyme assay. Smilax china and Sanguisorba officinalis showed potent anti-PKC activity. Campsis grandiflora and Galla Halepensis showed moderate inhibitory effect on PKC.

Keywords