약학회지 (YAKHAK HOEJI)
- 제36권4호
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- Pages.321-325
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
테오필린과 페플록사신과의 상호작용
Interaction of Theophylline and Pefloxacin
- Chang, Il-Hyo (College of Pharmacy, Chosun University) ;
- Choi, Jun-Shik (College of Pharmacy, Chosun University) ;
- Lee, Jin-Hwan (College of Pharmacy, Chosun University)
- 발행 : 1992.08.29
초록
Pharmacokinetic interaction of theophylline with pefloxacin following i.v. administrations was investigated in rabbits. Pefloxacin was coadministrated at doses of 10 and 20 mg/kg or previously administered for 6 days 10 and 20 mg/kg. Plasma concentration and AUC of theophylline were increased significantly (p<0.05) and the renal clearance
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