YAKHAK HOEJI (약학회지)
- Volume 36 Issue 2
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- Pages.120-125
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Characterization of Adsorbents for the Solid-Phase Extraction of Trace Diphenylhydantoin from Biological Samples
생체시료로 부터 미량 디페닐히단토인의 고상추출에 사용될 흡착제의 특성
- Kim, Kyoung-Rae (College of Parmacy, Sung Kyun Kwan University) ;
- Lee, Kyoung-Won (College of Parmacy, Sung Kyun Kwan University) ;
- Shim, Weon-Hee (College of Parmacy, Sung Kyun Kwan University)
- Published : 1992.04.29
Abstract
Ths sorption and desorption properties of four different solid adsorbents were evaluated for the trace enrichment of diphenylhydantoin from biological samples. Graphitized carbon black(GCB) gave the highest adsorption coefficient. And among the organic solvents examined, methanol gave the highest desorption coefficient. Using the GCB column, the optimum elution volume of the eluting solvent was evaluated from the breakthrough curve of diphenylhydantoin. The usefulness of GCB as the solid adsorbent was examined for the solid-phase extraction of diphenylhydantoin from serum in the concentration range of