YAKHAK HOEJI (약학회지)
- Volume 36 Issue 1
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- Pages.12-16
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Facile Synthesis of 2-(p-Methylallylaminophenyl)propionic Acid (Alminoprofen)
2-(p-메틸알릴아미노페닐)프로판산의 합성
- Choi, Hong-Dae (Department of Chemistry, Dongeui University) ;
- Yun, Ho-Sang (Department of Chemistry, Dongeui University) ;
- Kang, Byung-Won (Department of Chemistry, Dongeui University) ;
- Ma, Jung-Joo (Department of Chemistry, Dongeui University) ;
- Son, Byeng-Wha (Department of Chemistry, National Fisheries University of Pusan)
- Published : 1992.02.29
Abstract
A new method for the synthesis of alminoprofen, which is a non-steroidal antiinflammatory agent, was described. Ethyl 2-phenyl-propionate(4) was prepared by Friedel-Crafts reaction of benzene with ethyl
Keywords
- Alminoprofen;
- a non-steroidal antiinflammatory agent;
- Friedel-Crafts reaction;
- methylation;
- desulfurization;
- nitration;
- reduction;
- hydrolysis