Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Formaldehyde 가스 흡입에 의한 마우스의 급성독성 및 소핵 유발성에 관한 연구

  • Kim, Choong-Yong (Toxicology Research Center, Korea Research Institute of Chemical Technology) ;
  • Kim, Kyun (Toxicology Research Center, Korea Research Institute of Chemical Technology) ;
  • Shim, Jeom-Soon (Toxicology Research Center, Korea Research Institute of Chemical Technology) ;
  • Kim, Yong-Hwa (Toxicology Research Center, Korea Research Institute of Chemical Technology) ;
  • Roh, Jung-Koo (Toxicology Research Center, Korea Research Institute of Chemical Technology)
  • 김충용 (한국화학연구소 안정성연구센터) ;
  • 김균 (한국화학연구소 안정성연구센터) ;
  • 심점순 (한국화학연구소 안정성연구센터) ;
  • 김용화 (한국화학연구소 안정성연구센터) ;
  • 노정구 (한국화학연구소 안정성연구센터)
  • Published : 1991.06.01
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Abstract

The acute and genetic effect of formaldehyde on mice through inhalation route was studied. The Riley's chamber with one stack of cage was used for the exposure and the micronucleus test was performed under unprecedently maximum exposure concentration. LC50's of formaldehyde in mice by whole body exposure for 4 hours were 105.5 ppm with 95% confidence interval of 72.6 ppm and 143.2 ppm for male, and 159.2 ppm with 95% confidence interval of 116.5 ppm and 272.7 ppm for female. Cinicial symptoms by acute exposure were salivation, lacrimation, and abnormal respiration.

Keywords

References

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