Journal of Pharmaceutical Investigation
- 제21권2호
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- Pages.73-78
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- 1991
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
푸로푸라놀롤 좌제 개발에 관한 연구
Study on the Design of Propranolol Rectal Suppository
- Kim, Ga-Na (College of Pharmacy, Chosun University) ;
- Choi, Jun-Shik (College of Pharmacy, Chosun University) ;
- Lee, Jin-Hwan (College of Pharmacy, Chosun University)
- 발행 : 1991.06.20
초록
The influence of different suppository bases on the rectal absorption and the dissolution rate of propranolol was investigated. The bioavailability of propranolol in rectal suppository was determined by comparing the area under the concentration-time curves(AUC) for oral administration with rectal suppositories in rabbits. The dissolution
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