Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Hepatoprotective Effects of Andrographis paniculata against Carbon Tetrachloride-Induced Liver Damage

  • Rana, A.C. (College of Pharmacy, Shri Govindram Seksaria Institute of Technology and Science) ;
  • Avadhoot, Y. (College of Pharmacy, Shri Govindram Seksaria Institute of Technology and Science)
  • Published : 1991.03.01
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Abstract

Alcoholic extract of the leaves of Andrographis paniculata Ness (=AAP) was obtained by cold maceration. A dose of 300 mg/kg $(1/6of\;LD_{50})$ of the extract was selected to study hepatoprotective action against carbon tetrachloride-induced liver damage. The extract was found to be effective in preventing liver damage which was evident by morphological, biochemical and functional parameters.

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