Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Hepatoprotective Effect of Vitex negundo against Carbon Tetrachloride-Induced Liver Damage

  • Avadhoot, Y. (College of Pharmacy, Shri Govindram Seksaria Institute of Technology & Science) ;
  • Rana, A.C. (College of Pharmacy, Shri Govindram Seksaria Institute of Technology & Science)
  • Published : 1991.03.01
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Abstract

Alcoholic extract of the seeds of Vitex negundo Linn. was obtained by cold maceration. A dose of 250 mg/kg $(1/6\;of\;LD_{50})$ of the extract was selected to study the hepatoprotective action against carbon tetrachloride-induced liver damage. The extract was found to be effective in preventing liver damage which was evident by morphological, biochemical and functional parameters.

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