The Korean Journal of Nuclear Medicine (대한핵의학회지)
- Volume 24 Issue 2
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- Pages.215-221
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- 1990
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- 1225-6714(pISSN)
A Study on Synthesis of $^{99m}Tc-HMPAO$ as A Brain Perfusion Agent and Its Distribution
뇌혈류 평가용 $^{99m}Tc-HMPAO$ 합성 및 분포에 관한 연구
-
Lee, Myung-Chul
(Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Lee, Bum-Woo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
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Chung, June-Key
(Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Cho, Bo-Youn (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University) ;
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Jeong, Jae-Min
(Department of Nuclear Medicine, Seoul National University Hospital) ;
- Yeom, Mi-Kyung (Department of Nuclear Medicine, Seoul National University Hospital) ;
-
Hong, Mee-Kyoung
(Department of Nuclear Medicine, Seoul National University Hospital) ;
- Choi, Seok-Rye (Central Laboratory, Seoul National University Hospital)
-
이명철
(서울대학교 의과대학 내과학교실) ;
- 이범우 (서울대학교 의과대학 내과학교실) ;
-
정준기
(서울대학교 의과대학 내과학교실) ;
- 조보연 (서울대학교 의과대학 내과학교실) ;
- 고창순 (서울대학교 의과대학 내과학교실) ;
-
정재민
(서울대학병원 핵의학과) ;
- 염미경 (서울대학병원 핵의학과) ;
-
홍미경
(서울대학병원 핵의학과) ;
- 최석례 (서울대학병원 중앙연구실)
- Published : 1990.11.25
Abstract
HM-PAO was synthesized by two step reaction. d, 1-HM-PAO was separated from the racemic product by fractional recrystalization in ethylacetate, and the chemical structure and purity was confirmed by proton NMR spectroscopy. The synthesized 0, 1-HM-PAO was labeled with
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