The Korean Journal of Mycology (한국균학회지)

The Korean Society of Mycology (한국균학회)
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Studies on the Anticomplementary Activity of Korean Higher Fungi

한국산 고등균류의 항보체활성 효과에 관한 연구

  • Jeong, Hoon (Central Institute of Research, Il Yang Pharmaceutical Co. Ltd.) ;
  • Lee, June-Woo (Central Institute of Research, Il Yang Pharmaceutical Co. Ltd.) ;
  • Lee, Kweon-Haeng (Central Institute of Research, Il Yang Pharmaceutical Co. Ltd.)
  • 정훈 (일양약품(주)중앙연구소) ;
  • 이준우 (일양약품(주)중앙연구소) ;
  • 이권행 (일양약품(주)중앙연구소)
  • Published : 1990.09.30
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Abstract

Anticomplementary activity of 61 strains of Korean higher fungi was screened for immunostimulation. Extracts from 11 of 61 strains including 5 of Ganoderma lucidum, 3 of Lentinus edodes, 2 of Cordyceps sp. and 1 of Agaricus campestris, showed higher anticomplementary activity than krestin which was immunopotent extract from Japanese Coriolus versicolor. The most potent anticomplementary activity was found with extract from Lentinus edodes IY105 whose complement consumption was 31.7%.

국내에서 자생하는 61주의 고등균류로부터 면역증강효과를 검색하기 위해 이들로부터 성분을 분리하여 이들의 항보체활성을 측정한 결과, krestin의 보체활성도인 20.6%보다 우수한 보체활성 효과를 나타낸 것은 11주 였으며, 이 중에는 Ganoderma lucidum 5주, Lentinus edodes 3주, Cordyceps sp. 3주 및 Agaricus campestris 1주이다.

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