Toxicological Research
- 제5권2호
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- Pages.151-166
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- 1989
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
INHIBITORY EFFECTS OF RED GINSENG EXTRACT ON DEVELOPMENT OF PEPSINOGEN 1 DECREASED PYLORIC GLANDS IN RAT STOMACH
초록
This study was carried out to investigate the effect of red ginseng extract on development of pepsinogen 1 decrased pyloric glands in experimental stomach carcinogenesis in Sprague-Dawley male rats. Sequential quantitative analyses (by ABC immunohistochemical staining) were made of pepsinogen 1 decreased pyloric glands (PDPG) after treating rats first with a single dose (160 mg/kg) N-methyl-N'-nitrosoguanidine (MNNG) and then with N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG) (100ug/ml of drinking water) as a second gastric carcinogen (or promoter).
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