YAKHAK HOEJI (약학회지)
- Volume 33 Issue 6
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- Pages.361-364
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- 1989
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Synthesis of Acyclonucleosides (3) -Synthesis of Ribavirin Derivatives-
Acyclonucleoside 류의 합성(3) -Ribavirin 유도체의 합성-
- Moon, Hyung-Ryong (College of Pharmacy, Seoul National University) ;
- Yang, Jae-Wook (College of Pharmacy, Seoul National University) ;
- Kim, Moon-Hwan (College of Pharmacy, Seoul National University) ;
- Chun, Moon-Woo (College of Pharmacy, Seoul National University) ;
- Chung, Won-Keun (College of Pharmacy, Seoul National University)
- Published : 1989.12.28
Abstract
The Synthesis of acyclic derivatives of ribavirin (2'-azido and halo seco derivatives) for the development of new antiviral agents is described. These acyclic nucleosides are synthesized from ribavirin by the method of ring opening reaction of sugar moietry.