Effects of Malotilate on Levels of Ethanol and Acetaldehyde in Blood

혈중 Ethanol 및 Acetaldehyde의 농도에 미치는 Malotilate의 영향

  • 허인회 (중앙대학교 약학대학) ;
  • 이상준 (중앙대학교 약학대학) ;
  • 주왕기 (강원대학교 약학과) ;
  • 허문영 (강원대학교 약학과) ;
  • 김형춘 (중앙대학교 의과대학 병리학교실) ;
  • 송계용 (중앙대학교 의과대학 병리학교실)
  • Published : 1987.12.01

Abstract

A gas chromatographic utilizing procedure headspace gas analysis is performed to study effect of malotilate on levels of ethanol and its metabolite acetaldehyde in a blood sample from the rat. The concentrations of ethanol and acetaldehyde were determined simultaneously at 1, 3, and 6h after ethanol administration. Our results would suggest the malotilate could promote clearances of ethanol and acetaldehyde in blood, and could accelerate it, especially, in $CCl_4$ pretreated rats.

Keywords

References

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