Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
권호 표지
DOI QR코드

DOI QR Code

Studies on the Formation and Stability of Colloids (I): Perturbation of Micelle Formation of Sodium Deoxycholate by Amides

  • Published : 1986.10.20
Download PDF
⟨ Previous Next ⟩

Abstract

The critical micelle concentration (CMC) of sodium deoxycholate (NaDC) and the effects of amides on the micellization processes have been studied by fluorometric technique using pyrene as a probe. The addition of amides as cosolvent destabilized the NaDC micelle and increased the CMC. The order of effectiveness for the perturbation of NaDC micelle was N-methylacetamide ${\ge}$ DMF > acetamide > formamide, which is the order of hydrophobicity of the amines. This indicated that the effect of amides on the micellization processes of NaDC arises from diminution of the hydrophobic effect. The electrostatic repulsion between ionic head groups in the NaDC micelle appeared to be much less than that in aliphatic ionic micelle. This was also revealed in the weaker dependence of the CMC on ionic strength. The premicellar association of NaDC was not significantly involved in the micellization processes of the bile salt.

Keywords

References

  1. The Bile Acids: Chemistry, Physiology, and Metabolism v.I D.M. Small;P.P. Nair(ed.);D. Kirtchevsky(ed.)
  2. Bull. Chem. Soc. Jpn. v.49 G. Sugihara;M. Tanaka
  3. J. Phys. Chem. v.81 D.G. Oakenfull;L.R. Fisher
  4. J. Phys. Chem. v.84 L.R. Fisher;D.G. Oakenfull
  5. J. Phys. Chem. v.82 R, Zana
  6. J. Phys. Chem. v.89 R. Zana;D. Giveli
  7. J. Phys. Chem. v.84 M. Vadnere;R. Natarajan;S. Lindenbaum
  8. J. Soln. Chem. v.10 N. Rajagopalan;M. Vadnere;S. Lindenbaum
  9. Ber. Bunsenges. Phys. Chem. v.86 B. Sesta;C. La Mesa;A. Bonincontro;C. Cametti;A. Di Biasio
  10. Ber. Bunsenges. Phys. Chem. v.85 B. Sesta;C. La Mesa;A. Bonincontro;C. Cametti;A. Di Biasio
  11. Bull. Chem. Soc. Jpn. v.51 T. Kunitake;Y. Okahata
  12. J. Kor. Chem. Soc. v.26 J.W. Park;J.-S. Kim
  13. J. Phys. Chem. v.71 M.F. Emerson;A. Holtzer
  14. J. Phys. Chem. v.89 M. Almgren;S. Swarup;J.E. Lofroth
  15. J. Phys. Chem. v.90 N.J. Turro;P.L. Kuo;P. Somasundaran;K. Wong
  16. J. Phys. Chem. v.86 G. Sugihara;K. Yamakawa;Y. Murata;M. Tanaka
  17. J. Coll. Interface Sci. v.78 D.C. Thomas;S.D. Christian
  18. J. Biol. Chem. v.258 A. Roda;A.F. Hofmann;K.J. Mysels
  19. J. Coll. Interface Sci. v.95 C.J. O'Connor;B.T. Ch'ng;R.G. Wallace
  20. The hydrophobic Effect: Formation of Micelles and Biological Membranes C. Tanford
  21. The hydrophobic Effect: Formation of Micelles and Biological Membranes C. Tanford

Cited by

  1. Aggregation and Adsorption Behaviors of Sodium Deoxycholate in Water–Ethylene Glycol Medium vol.83, pp.11, 1986, https://doi.org/10.1246/bcsj.20100152
  2. Effect of sodium salicylate, sodium oxalate, and sodium chloride on the micellization and adsorption of sodium deoxycholate in aqueous solutions vol.357, pp.2, 1986, https://doi.org/10.1016/j.jcis.2011.02.020