생약의 수치(修治)에 따른 약효연구(제3 보) : 백작약(白芍藥)이 중추신경계 및 적출장관에 미치는 영향

Studies on Efficacy of Crude Drug by Processing(III): Effect of Paeoniae Radix alba on CNS and Isolated Ileum

Pharmacological activities of Paeoniae Radix alba were studied with water extract (F-I), parched preparation (F-II) and 25% ethanol-treated preparation (F-III) of it. The results were summerized as follows; 1) Analgesic actions were recognized with F-I, F-II and F-III. 2) Sedative actions were recognized with F-I and F-III. 3) Prolonged effect of sleeping time were recognized significantly with F-I and F-III. 4) Antipyretic actions were recognized with F-1, F-II and F-III in rabbits. 5) F-I, F-II and F-III showed the antagonic action against contraction of isolated-ileum induced by acetylcholine, barium chloride and histamine in mice and guinea-pigs.