희석(稀釋)된 수종(數種)의 근관소독제(根管消毒劑) 및 근관세척제(根管洗滌劑)가 백서피하조직(白鼠皮下組織)에 미치는 영향(影響)에 대(對)한 병리조직학적(病理組織學的) 연구(硏究)

HISTOPATHOLOGIC STUDY ON THE RAT SUBCUTANEOUS TISSUE FOLLOWING EXPOSURE TO VARIOUS CONCENTRATIONS OF CANAL IRRIGANT AND CANAL MEDICAMENTS

The purpose of this study is to estimate the reaction of rat subcutaneous tissues following exposure to the various concentrations of formocresol (100, 50, 20%), eugenol (100, 75, 50%), and sodium hypochlorite. (5, 3.5, 0.5%) The results were as follows: 1. As the concentration of formocresol was decreased, the inflammatory reaction was decreased conspicuously. 2. The inflammatory reaction of 100% eugenol was appeared to be similar to that of 75% eugenol. The inflammatory reaction of 50% eugenol was decreased conspicuously. 3. No significant differences were found in inflammatory response between 3.5% and 5% sodium hypochlorite. 4. The inflammatory reaction of 0.5% sodium hypochlorite was mild and appeared to be similar to that of saline solution in 7 days.