The Korean Journal of Physiology

The Korean Physiological Society (대한생리학회)
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Depressor Responses to Intravenously Administered Perrillae Folium Juice (PFJ) in Cats

임엽(荏葉)(Perillae Folium)의 혈압강하 작용

  • Sohn, Young-Zoo (Department of Physiology, School of Medicine, Hanyang University) ;
  • Shin, Hong-Kee (Department of Physiology, School of Medicine, Hanyang University) ;
  • Kim, Kee-Soon (Department of Physiology, School of Medicine, Hanyang University)
  • 손영주 (한양대학교 의과대학 생리학교실) ;
  • 신홍기 (한양대학교 의과대학 생리학교실) ;
  • 김기순 (한양대학교 의과대학 생리학교실)
  • Published : 1982.12.31
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Abstract

The present study was undertaken to investigate effects of Perillae Folium juice on the respiration and blood pressure in cats. Also studied was the mechanism of depressor action of PFJ. The results obtained are as follows; 1) Following administration of 0.2 ml/kg, 0.4 ml/kg and 0.6 ml/kg PFJ into cats the maximum depressor responses observed were 48.5+3.6 mmHg, 56.8+4.3 mmHg and 71.1+2.9 mmHg respectively. 2) Depressor responses to PFJ were blocked makedly by atropine and partially by propranolol. Therefore it is strongly suggested that depressor action of PFJ results mainly from cholinergic effect and partly from activity of ${\beta}-receptor$. 3) After administration of PFJ into cats tachypnea preceded by a short period of apnea was observed invariably.

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