The Korean Journal of Pharmacology (대한약리학회지)

The Korean Society of Pharmacology (대한약리학회)
권호 표지

Clinical Report for Piroxicam in Orthopedic Field

류마치양 관절염 및 퇴행성관절염에 대한 Piroxicam의 사용경험

  • Youn Sung-Ho (Dept.of Orthopedic Surgery, Choong-Nam National Univ) ;
  • Rhee Kwang-Zin (Dept.of Orthopedic Surgery, Choong-Nam National Univ) ;
  • Ahn Sang-No (Dept.of Orthopedic Surgery, Choong-Nam National Univ)
  • 윤승호 (충남의대 부속병원 정형외과학교실) ;
  • 이광진 (충남의대 부속병원 정형외과학교실) ;
  • 안상노 (충남의대 부속병원 정형외과학교실)
  • Published : 1979.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

Piroxicam is known to be a new nonsteroidal anti-inflammatory drug which has anti-inflammatory, antiedema, antigranuloma and analgesic activities through the mechanism of inhibition of prostaglandin synthetase. Clinical survey for piroxicam was carried cut on 40 cases of rheumatoid arthritis and 30 cases of degenerative arthritis who visited University Hospital from Feb. to June, 1979. Following results could be obtained: 1) In rheumatoid and degenerative arthritis, the effect of piroxicam was significant in decrease of joint pain, shortening of duration of morning stiffness, decrease in number of swollen joints, improvement of joint stiffness, decrease of E.S.R., increase of mean grip strength and decrease of articular index. 2) Side effects, almost all in G-I troubles were encountered in 6 cases in 40 cases of rheumatoid arthritis and 4 cases in 30 cases of degenerative arthritis.

Keywords