Korean Journal of Pharmacognosy (생약학회지)
- Volume 7 Issue 2
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- Pages.119-121
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- 1976
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Effect of Ginseng Saponin on the Skin
인삼(人蔘) Saponin이 피부(皮膚)에 미치는 영향(影響)
- Kim, Nak-Doo (College of Pharmacy, Seoul National University) ;
- Woo, Lin-Keun (College of Pharmacy, Seoul National University)
- Published : 1976.06.15
Abstract
To investigate untoward effects which might be produced by local application of Ginseng saponin, sensitization test and eye irritation test were performed in guinea pigs and rabbits. Any reaction on the skin was not found at a dose of 0.1ml of 0.1% solution in sensitization test. Instillation of Ginseng saponin (0.1ml of 1.0% and 10% soultion) into the right eye of rabbits, did not produce any irritation. Median lethal dose of the total saponin in mouse was 695 mg/kg by i.p. and 1490mg/kg by s.c. injection.
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