대한약리학회지 (The Korean Journal of Pharmacology)
- 제5권2호
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- Pages.115-119
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- 1969
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- 0377-9459(pISSN)
볼낙(Sebastes inermis) 방광(膀胱)의 Adrenotropic Receptor에 관(關)한 연구(硏究)
Studies on the Adrenotropic Receptors of the Isolated Urinary Bladder from Sebastes Inermis
- Sohn, Yong-Seuk (Department of Pharmacology, College of Medicine, Pusan National University) ;
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Hong, Ki-Whan
(Department of Pharmacology, College of Medicine, Pusan National University) ;
- Park, Jung-Yang (Department of Pharmacology, College of Medicine, Pusan National University)
- 발행 : 1969.12.30
초록
The authors studied the adrenotropic receptors of isolated urinary bladder from Sebastes inermis, using adrenergic activators such as epinephrine, nor-epinephrine, isoproterenol and phenylephrine and adrenergic blocking agents such as phenoxybenzamine, pronethalol and propranolol. The studies have revealed the following results. 1) The spontaneous motility of isolated bladder from Sebastes inermis was inhibited by epinephrine nor-epinephrine, isoproterenol and phenylephrine. 2) The inhibitory effect of phenylephrine on the Sebastes inermis bladder was blocked by phenoxybensamine. 3) The inhibitory effect of isoproterenol was blocked by pronethalol and propranolol. 4) The effect of epinephrine and nor-epinephrine on the Sebastes inermis bladder was usually not blocked by either kind of blocking agent alone, but was blocked by a combination of
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