Acknowledgement
본 연구는 수원대학교 교내연구진흥기금의 지원에 의해 이루어진 결과로 이에 감사드립니다.
Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 2022.09a
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- Pages.97-97
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- 2022
Whitening Effects of Crataegus pinnatifida bunge Fruit Extracts
크라테구스 열매 추출물의 미백효능
- Hyunji Kim (Department of Biotechnology, The University of Suwon) ;
- Juhee Song (Department of Biotechnology, The University of Suwon) ;
- Kunjung Chung (Department of Biotechnology, The University of Suwon) ;
- Minkyung Jang (Department of Biotechnology, The University of Suwon) ;
- Kyung-A Choi (National Institute of Medical Welfare, Kangnam University) ;
- June Hyun Kim (Department of Biotechnology, The University of Suwon)
- 김현지 (수원대학교 바이오공학과) ;
- 송주희 (수원대학교 바이오공학과) ;
- 정근정 (수원대학교 바이오공학과) ;
- 장민경 (수원대학교 바이오공학과) ;
- 최경아 (강남대학교 의료복지연구소) ;
- 김준현 (수원대학교 바이오공학과)
- Published : 2022.09.27
Abstract
The fruit of the Crataegus pinnatifida bunge has been known to have a role as a digestive stimulant, and is used for postpartum abdominal pain and women's menstrual pain. It is used for coronary artery disease, angina pectoris, hypertension and hyperlipidemia. Ascorbic acid, hydroquinone, retinoids, alpha-hydroxy acids, kojic acid, azelaic acid have been used for cosmetic whitening and medical depigmentation. To determine whether Crataegus pinnatifida bunge fruit also has whitening and depigmentation effect, tyrosinase inhibition assay was performed with American Crataegus pinnatifida Bunge ethanol extracts, Korean Crataegus pinnatifida Bunge (Cra) ethanol extracts and Arbutin as a positive control as previously described by Korean FDA guideline. Korean Cra fruit ethanol extracts were 1.87 fold more inhibitory function to tyrosinase activity than American Cra in the experimental condition that inhibitory function to tyrosinase activity of Korean Cra Arbutin is 81.8% when compared to that of the standard control Arbutin as 100%. These results suggest that ethanol extracts of Crataegus pinnatifida bunge have significant whitening effects and may provide the basis for development of cosmetic whitening agent and medical depigmentation applications.
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