Proceedings of the KSME Conference (대한기계학회:학술대회논문집)
- 2007.05b
- /
- Pages.3187-3190
- /
- 2007
Flow Characteristics of Elastin-Like Polypeptide(ELP) Coated Packed Bed
온도 감응성 폴리펩티드로 표면 처리된 충전층의 유동 특성
-
Kim, Duck-Jong
(Korea Institute of Machinery and Materials)
;
- Lee, Jong-Hwan (Seoul National University) ;
-
Park, Sang-Jin
(Korea Institute of Machinery and Materials)
;
- Hyun, Jin-Ho (Seoul National University)
- Published : 2007.05.30
Abstract
Elastin-Like polypeptide (ELP) composed of elastin-based repeating units is an artificial biomaterial which is biocompatible and non-immunogenic. ELP shows a characteristic inverse phase transition between hydrophobic and hydrophilic phase by external stimuli such as salt, pH and temperature. In this study, ELP coated PS (polystyrene) beads are packed in tubing and the thermo -responsive flow characteristics of the packed bed are investigated. Preliminary test results show that the control of the fluid flow can be achieved by using the temperature driven phase transition effect of the ELP coated beads in a microchannel.