Proceedings of the Korean Society of Precision Engineering Conference (한국정밀공학회:학술대회논문집)
- 2005.06a
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- Pages.668-671
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- 2005
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- 2005-8446(pISSN)
Carbon Nanotube DNA Bioconjugates as Nano-Bio Markers
탄소 나노튜브와 DNA와의 결합을 통한 나노-바이오 마커 응용
- Hwang Eung-Soo (Microbiol. & Immunol. Dept. SNUCM) ;
- Chengfan Cao (Mechanical Eng. Dept. SKKU) ;
- Hong Sang-Hyun (Mechanical Eng. Dept. SKKU) ;
- Jung Hye-Jin (Microbiol. & Immunol. Dept. SNUCM) ;
- Cha Chang-Yong (Microbiol. & Immunol. Dept. SNUCM) ;
-
Choi Jae-Boong
(Mechanical Eng. Dept. SKKU)
;
- Kim Young-Jin (Mechanical Eng. Dept. SKKU) ;
-
Baik Seung-Hyun
(Mechanical Eng. Dept. SKKU)
- 황응수 (서울대학교 의과대학) ;
- 조승범 (성균관대학교 기계공학과) ;
- 홍상현 (성균관대학교 기계공학과) ;
- 정혜진 (서울대학교 의과대학) ;
- 차창용 (서울대학교 의과대학) ;
-
최재붕
(성균관대학교 기계공학과)
;
- 김영진 (성균관대학교 기계공학과) ;
-
백승현
(성균관대학교 기계공학과)
- Published : 2005.06.01
Abstract
Carbon nanotubes exhibit strong fluorescence emissions in the region of near infrared regions where most biomolecules are transparent. Such signals are highly sensitive to environment variations as well as adsorption of specific biomolecules. In this research, single walled carbon nanotubes(SWNTs) are assembled with different types of DNAs and used to target specific types of DNAs. Dot blot investigations and corresponding raman spectroscopy observations demonstrated excellent selectivity of carbon nanotube-DNA bioconjugates. The results show possibility of using SWNT as generic nano-bio markers for precise detection of different kinds of genes.