Expression of Human Type II Collagen Gene in the Milk of Transgenic Mice

  • Kenji Naruse (Research Center for Transgenic and Cloned Pigs, Chungnam National University) ;
  • Yoo, Seung-Kwon (Division of Biotechnology and Genetic Engineering, Korea University) ;
  • Park, Yoon-Jae (Department of Animal Science & Technology, Seoul National University) ;
  • Jin, Dong-Il (Research Center for Transgenic and Cloned Pigs, Chungnam National University)
  • Published : 2004.06.01

Abstract

Collagen has been widely studied for medical applications. Previous studies have shown that the bovine β-casein promoter were able to drive cell-specific and hormone-dependent expression to a mouse mammary cell line but failed to induce accurate expression to the mammary gland. of transgenic mice. (omitted)

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