Stomach Cancer Cell Lysis in PBS with Conductivity and Osmotic-Pressure Control

용액 전도도 및 삼투압 조절된 PBS에서의 위암 세포 전기 분해

  • Kim, Min-Soo (School of Electrical Engineering & Computer Science, Seoul National University) ;
  • Lee, Kook-Nyung (School of Chemical Engineering, Seoul National University) ;
  • Cho, Su-Hyung (School of Chemical Engineering, Seoul National University) ;
  • Kim, Byung-Gee (School of Chemical Engineering, Seoul National University) ;
  • Kim, Yong-Kweon (School of Electrical Engineering & Computer Science, Seoul National University)
  • 김민수 (서울대학교 전기 컴퓨터 공학부) ;
  • 이국녕 (서울대학교 응용화학부) ;
  • 조수형 (서울대학교 응용화학부) ;
  • 김병기 (서울대학교 응용화학부) ;
  • 김용권 (서울대학교 전기 컴퓨터 공학부)
  • Published : 2004.07.14

Abstract

Cancer cell lysis at pulsed DC is realized using micromachined electrodes. In this research, quantitative analyses are performed on cell lysis results. The cell volume increasing at the pulses applied are analyzed in different medium conditions on osmotic pressure and conductivity, and the cell lysis procedures are studied in detail experimentally. Phosphate buffered saline (PBS) is used as the medium. To change the conductivity of PBS, NaCl concentration of PBS is adjusted, and inositol is used with PBS to control the effects of the osmotic pressure to cell lysis performance.

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