대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.92.2-93
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- 2003
Oxyresveratrol Derivative Compound DMPB Act as Potent Dipigment agent in Brown Guinea Pig Skin
- Choi, Sang-Yoon (Gradurate School of East-West Medical Science, Kyunghee University) ;
- Kim, Sang-Hee (Natural Products Reserch Institute, Seoul Natioal University) ;
- Hwang, Jae-Sung (Skin Reserch Institute, Amore-Pacific Cor) ;
- Kim, Ho-Cheol (Skin Reserch Institute, Amore-Pacific Cor) ;
- Kim, Sun-Yeou (Skin Reserch Institute, Amore-Pacific Corp)
- 발행 : 2003.10.01
초록
This study with the object of reported to depigment agent, oxyresveratrol derivative, compound DMPB. Compound DMPB with a two methoxy groups and modified connection chain. It was synthesized in accordance with a simple combination process. Compound DMPB exhibits depigmentaion ability on ultraviolet B-induced hyperpigmention of the brown guinea pig skin. In addition, this Compound exhibited 30% inhibitory effect of melanin generation without cell toxicity as a result of the treatment with 100 ppm in melan-a cells. (omitted)
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