Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.219.1-219.1
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- 2003
Differential regulation of gene expression by RNA polymerase II in response to DNA damage
- Heo, Jeong-Hwa (Lab. of Biochem. ＆ Mol. Biol., College of Pharmacy, Sungkyunkwan University) ;
- Han, Jeung-Whan (Lab. of Biochem. ＆ Mol. Biol., College of Pharmacy, Sungkyunkwan University) ;
- Lee, Hyang-Woo (Lab. of Biochem. ＆ Mol. Biol., College of Pharmacy, Sungkyunkwan University) ;
- Cho, Eun-Jung (Lab. of Biochem. ＆ Mol. Biol., College of Pharmacy, Sungkyunkwan University)
- Published : 2003.04.01
Abstract
RNA polymerase II (pol II) is known to cycle between hyperphosphorylated and hypophosphorylated forms during transcription cycle. These extensive phosphorylation/dephosphorylation event occurs in the C-terminal domain (CTD) of the largest subunit of pol II which consists of a tandemly repeated heptapeptide motif with consensus of YSPTSPS. (omitted)
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