Preparation and Properties of Silk Fibroin/Alginate Blend Sponges and its Application

  • Kweon, Hae-Yong (National Institute of Agricultural Science & Technology) ;
  • Lee, Kwang-Gill (National Institute of Agricultural Science & Technolog) ;
  • Yeo, Joo-Hong (National Institute of Agricultural Science & Technolog) ;
  • Woo, Soon-Ok (National Institute of Agricultural Science & Technolog) ;
  • Han, Sang-Mi (National Institute of Agricultural Science & Technolog) ;
  • Lee, Yong-Woo (National Institute of Agricultural Science & Technolog) ;
  • Lee, Jang-Hern (College of Veterinary Medicine, Seoul National University) ;
  • Ham, Tae-Won (College of Veterinary Medicine, Seoul National University) ;
  • Ki, Chang-Seok (School of Biological Resources and Materials Engineering, Seoul National University) ;
  • Park, Young-Hwan (School of Biological Resources and Materials Engineering, Seoul National University)
  • Published : 2003.10.01

Abstract

Silk fibroin (SF) is one of the typical protein polymer produced by silkworm, Bombyx mori. SF has been used as textile fiber and surgical suture fur thousands of years due to its unique gloss, handle, and mechanical properties. Recently, SF has been intensively studied to diverse usage for biotechlological and biomedical fields because of their reproducibility, environmental compatibility, non-toxicity, and biological compatibility. Based on its biocompatibility, the possible uses of regenerated SF have been proposed including substrate for cell culture[1], enzyme immobilization[2], and matrix for drug release[3]. (omitted)

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