Proceedings of the Korean Society of Veterinary Pathology Conference (한국수의병리학회:학술대회논문집)

Korean Society of Veterinary Pathology (한국수의병리학회)
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Time Course Development of Airway Remodeling in Mouse Chronic Asthma Model

  • Oh, Se-woong (Dept.. of Vet. Pathol., College of Vet. Med., Seoul National Univ.) ;
  • Park, Hae-sim (Dept. of Allergy and Clin. Immunol., Ajou Univ) ;
  • Kim, Dae-yong (Dept.. of Vet. Pathol., College of Vet. Med., Seoul National Univ.)
  • Published : 2003.10.01
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Abstract

Histological examination of biopsy or postmortem lung tissue from patients with asthma usually reveals thickened airway walls. This change is called airway remodeling, which is characterized by airway eosinophilia, hyperplasia of goblet cells and smooth muscle, and subepithelial fibrosis [1,2]. In this study, we investigated the time-course functional, morphological, biochemical changes of remodeling in a ovalbumin (OVA)-induced murine chronic asthma model. (omitted)

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