Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Bcl-Xl Enhances Resistence to Parkisonian Toxin Mpp+ in Nurr1-Induced Dopamine Neurons

  • Park, Chang-Hwan (Department of Microbiology, Hanyang University) ;
  • Kang, Jin-Sun (Department of Microbiology, Hanyang University) ;
  • Lee, Sang-Hun (Department of Biochemistry, College of Medicine, Hanyang University)
  • Published : 2003.10.01
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Abstract

In-vitro expanded CNS precursors provide a potentially unlimited source of dopamine (DA) neurons for the experimental treatment in Parkinson's disease. An efficient dopaminergic differentiation from CNS precursors in vitro is limited to mesencephalic precursors isolated from early embryonic ages (embryonic day 11.5 (E11.5)-E12.5).(omitted)

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