13-Week Oral Gavage Toxicity with Sophora Japonica Linne Seed Extract in Sd Rats

  • Lee, Jae-Hyung (School of Life and Food Sciences, Handong University) ;
  • Kim, Il-Yong (School of Life and Food Sciences, Handong University) ;
  • Hyun, Chang-Kee (School of Life and Food Sciences, Handong University)
  • Published : 2003.10.01

Abstract

In recent years. attention has focused on the application of the alkaline single cell gel electrophoresis (SCGE or Comet) assay in environmental mutagenesis. To evaluate the suitability of the assay as a monitoring. technique, the DNA damages in liver cells and erythrocytes of carp (Cyprinus carpio) exposed to benzo[${\alpha}$]pyrene (B[${\alpha}$]P) were estimated comparatively with the in vivo Comet assay and the micronucleus test (MNT).(omitted)

Keywords