Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.123-123
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- 2003
Involvement of P38 Mapk and Gap Junctional Intercellular Communication (Gjic) in 12-O-Tetradecanoyl Phorbol 13-Acetate-Induced Stellation of Neurosphere-Derived Cells
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Yang, Se-Ran
(Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University)
;
- Ahn, Nam-Shik (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
- Jung, Ji-Won (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
- Park, Joon-Suk (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
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Yoon, Byoung-Su
(Laboratory of Genetics, Department of Biology, College of Natural Science, Kyonggi University)
;
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Lee, Yong-Soon
(Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University)
;
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Kang, Kyung-Sun
(Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University)
- Published : 2003.10.01
Abstract
Primary cultures of rat fetus brain exhibit phenotypes of neuron, oligodendrocyte, and astrocyte from "neurospheres". To understand the role of mitogen-activated protein kinase (MAPK) cascade and gap junctional intercellular communication (GJIC) in the differentiation of neurosphere-derived astrocyte, we investigated the effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the cultured astrocyte morphology.(omitted)