Promotion of Liver Lesion Development in the Syrian Hamster by Deitary fat Following Multi-Organ Initiation is Inhibited by Dhea-S Administration

  • Park, Cheol-Beom (Special Toxicology Team, Biotoxtech) ;
  • Kim, Sun-Hee (Special Toxicology Team, Biotoxtech) ;
  • Shim, Young-Hee (Special Toxicology Team, Biotoxtech) ;
  • Kim, Dae-Joong (College of Vet. Med., Chungbuk National University) ;
  • Lee, Jong-Sung (Special Toxicology Team, Biotoxtech) ;
  • Park, Jong-Il (Special Toxicology Team, Biotoxtech) ;
  • Kang, Jong-Koo (College of Vet. Med., Chungbuk National University) ;
  • Moore, Malcome.A. (Experimental Pathology and chemotherapy division, National Cancer Center Research Institute) ;
  • Iroyuki, Tsuda.H. (Experimental Pathology and chemotherapy division, National Cancer Center Research Institute)
  • Published : 2003.10.01

Abstract

The influence of dietary supplementation with dehydroepiandrosterone-sulphate (DHEA-S) at 0.6% was investigated in male Syrian golden hamsters initiated by treatments with azoxymethane(AOM), and dihydroxy-di-n-propyl nitrosamine (DHPN), timed after transfer from a choline-deficient to a normal diet.(omitted)

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