Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.05a
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- Pages.103-104
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- 2003
Suppressive Effects of Experimental Liver Preneoplastic Lesions by Estrogen Treatment in Male Rats
- Park, Ki-Dae (National Institute of Toxicological Research, Korea Food ＆ Drug Administration) ;
- Han, Beom-Seok (National Institute of Toxicological Research, Korea Food ＆ Drug Administratio) ;
- Nam, Ki-Taek (National Institute of Toxicological Research, Korea Food ＆ Drug Administratio) ;
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Cho, Wan-Seob
(National Institute of Toxicological Research, Korea Food ＆ Drug Administratio)
;
- Park, Mi-Na (National Institute of Toxicological Research, Korea Food ＆ Drug Administratio) ;
- Kim, Se-Yl (National Institute of Toxicological Research, Korea Food ＆ Drug Administratio) ;
- Kang, Jin-Seok (Osaka City University) ;
- Ahn, Byeong-Woo (Chungbuk National University) ;
- Che, Jeong-Hwan (Agency for Defense Development) ;
- Lee, Kook-Yung (Cheju National University) ;
- Dong, Deuk-Jang (National Institute of Toxicological Research, Korea Food ＆ Drug Administration) ;
- Yang, Ki-Hwa (National Institute of Toxicological Research, Korea Food ＆ Drug Administration)
- Published : 2003.05.01
Abstract
The incidence of liver cancer is markedly sex-differentiated epidemiologically, with a much higher frequency in men than in women. In experimental animals, male have higher incidence of liver tumors than female in carcinogen-induced tumors as well as spontaneous ones. Our studies were investigated to examine the modifying effects of sex hormones in the proneoplastic lesions of liver on diethylnitrosamine (DEN) - induced hepatocarcinogenesis. (omitted)
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