대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.407.1-407.1
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- 2002
Development of Immunostrip for DDT Detection
- Hong, Ji-Youn (Bioanalysis ＆ Biotransformation Research Center) ;
- Kim, Joung-Hyun (Korea Institute of Science ＆ Technolog) ;
- Lee, Eun-Ah (Department of Chemistry Seoul Women′s University) ;
- Choi, Myung-Ja (Department of Chemistry Seoul Women′s University)
- 발행 : 2002.10.01
초록
To develop immunostrip of DDT (4.4'-dichlorodiphenyl-2.2,2-trichloroethane) and its metabolites, DDT derivatives (DDA-. DDHP-. DDCP-. DDHH-. and DDHHAP-) were conjugated to carrier proteins (OVA and BSA) and three DDT derivatives (DDA. DDHP. DDCP) were conjugated to KLH for the use of coating ligand and immunogen. respectively. To screen the immunoreactivity of antibody to DDT derivatives, the coating ligand was evaluated by a competitive ELISA and DDHP-OVA was selected. (omitted)
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