Neuroprotective effect of extract of Angelicae tenuissimae on ischemic damage after oxygen and glucose deprivation(OGD) in rat organotypic hippocampal slice

  • Son , Dong-Wook (Department of Pharmacology Seoul National University College of Medicine and Neurosciences Research Institute, Medical Research Center) ;
  • Lee, Jong-Seok (Department of Pharmacology Seoul National University College of Medicine and Neurosciences Research Institute, Medical Research Cente) ;
  • Lee, Pyeong-Jae (Department of Pharmacology Seoul National University College of Medicine and Neurosciences Research Institute, Medical Research Cente) ;
  • Kim, Jeong-Min (Department of Pharmacology Seoul National University College of Medicine and Neurosciences Research Institute, Medical Research Cente) ;
  • Kim, Yong-Sik (Department of Herbal Pharmacology, Graduate School of East-West Medical Science, Kyung He University) ;
  • Kim, Ho-Cheol (Department of Pharmacology Seoul National University College of Medicine and Neurosciences Research Institute, Medical Research Cente) ;
  • Kim, Sun-Yeou (Department of Pharmacology Seoul National University College of Medicine and Neurosciences Research Institute, Medical Research Center)
  • Published : 2002.10.01

Abstract

Angelicae tenuissimae ia a plant often used in traditional Korean medicine. It has been used as analgesic. antipyretic and anti-inflammatory agent. However its component and precise modes of neuropharmacological action have not been reported. In the present study, we investigated the protective effects of A. tenuissimae and it's component on ischemic damage induced by oxygen and glucose deprivation in rat hippocampal slice. (omitted)

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