Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.379.1-379.1
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- 2002
Screening of Compounds Isolated from the Roots of Juglans mandshurica for DNA Topoisomerases I and II Inhibitory Activity
- Li-Gao (College of Pharmacy, Yeungnam University) ;
- Mu, Ming-Lu (Department of Biochemistry College of Natural Sciences Yeungnam University) ;
- Seo, Chang-Seob (College of Pharmacy, Catholic University) ;
- Kim, Jae-Hyon (College of Pharmacy, Catholic University of Daeg) ;
- Kim, Hyo-Jin (College of Pharmacy, Catholic University of Daeg) ;
- Lee, Chong-Soon (College of Pharmacy, Catholic University of Daeg) ;
- Hee, Woo-Mi (College of Pharmacy, Catholic University of Daeg) ;
- Son, Jong-Keun (College of Pharmacy, Catholic University of Daegu)
- Published : 2002.10.01
Abstract
As described previously. we reported twenty two compounds including one naphthoquinone. eight diarylheptanoids, two tetralone. one sesquiterpenoid. one diarylheptanoid glucoside, two tetralone glucosides. one naphthalene carboxylic acid glucoside and six naphthalenyl glycosides were isolated from the roots of Juglans mandshurica (17-22). Here we report that al of these compounds and a known triterpene are tested for the inhibitory effects against DNA topoisomerases I and II activities. (omitted)
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