Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
- /
- Pages.326.1-326.1
- /
- 2002
Identification and characterization of a novel cancer/testis antigen gene
- Cho , Bom-Soo (Cancer Genomics Division, In2Gen Company) ;
- Lee, Dae-Yeon (Cancer Research Center, Seoul National University College of Medicin) ;
- Lim , Yoon (Cancer Research Center, Seoul National University College of Medicin) ;
- Park, Sae-Young (Cancer Research Center, Seoul National University College of Medicin) ;
- Lee, Ho-Soon (Cancer Research Center, Seoul National University College of Medicin) ;
-
Kim, Woo-Ho
(Cancer Research Center, Seoul National University College of Medicin)
;
-
Yang, Han-Kwang
(Cancer Research Center, Seoul National University College of Medicin)
;
-
Bang, Yung-Jue
(Cancer Research Center, Seoul National University College of Medicin)
;
- Jeoung , Doo-Il (Cancer Research Center, Seoul National University College of Medicine)
- Published : 2002.10.01
Abstract
We applied serological analysis of cDNA expression library technique to identify cancer-associated genes. We screened cDNA expression libraries of human testis and gastric cancer cell lines with sera of patients with gastric cancers. We identified a gene whose expression is testis-specific among normal tissues. We cloned and characterized this novel gene. It contains D-E-A-D box domain and encodes a putative protein of 630 amino acids with possible helicase activity. It showed wide expression in various cancer tissues and cancer cell lines. (omitted)
Keywords