Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.260.2-260.2
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- 2002
Antidiabetic effect and mechanisms of SPH-2 in db/db mice
- Kang, Kwi-Man (School of Pharmacy, Kyung Hee University) ;
- Cho, Hee-Jae (Institute of Science and technology CJ corp.) ;
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Chung, Sung-Hyun
(School of Pharmacy, Kyung Hee University)
- Published : 2002.10.01
Abstract
SPH-2 is a herbal medicine composing oriental prescription. We have studied the antidiabetic effect and mechanism of SPH-2 in insulin-resistant diabetic db/db mice. Mice were grouped and treated for 3 weeks as follows: control group was administrated with tap water orally: treated group was administrated with SPH-2 orally at dose of 500 mg/kg. SPH-2 lowered plasma glucose level by 43% as compared to the diabetic control. Total cholesterol. triglyceride and free fatty acid were all reduced in SPH-2 treated group. (omitted)
Keywords